London, 20 November 2025 — PolyModels Hub has raised £7 million in a Series A round led by Molten Ventures, with participation from Marathon Venture Capital, to accelerate the digital transformation of biopharma process development.

The new funding will enable PolyModels Hub to expand its engineering and product teams, enhance its core platform, and reach more pharmaceutical organizations worldwide. The company will focus on developing scalable solutions for process and regulatory workflows, making it easier for customers to adopt and benefit from its technology.

Rethinking how medicines are made

Developing a new drug typically costs around $2.5 billion, with roughly a quarter of that — about $650 million — spent on process development alone. Across the hundreds of therapies progressing through the pipeline each year, this represents a vast opportunity to make drug development faster, more efficient, and more reproducible.

Our platform, ModelFlow, brings together advanced modeling, simulation, and workflow management in one integrated digital environment. It allows scientists and engineers to design, test, and refine manufacturing processes faster, connecting data and expertise across teams and departments.

By combining physics-based and AI-driven models with structured, traceable workflows, ModelFlow helps organizations reduce experimental burden, enhance process understanding, and make confident decisions earlier in development.

From complexity to clarity

In conventional settings, scientists rely on dozens or even hundreds of laboratory experiments to optimize a single process — work that can take weeks or months to complete. In early deployments, ModelFlow has reduced experimental workloads by more than 90%, turning 100-experiment workflows into fewer than ten while maintaining or improving scientific robustness.

These results speak to a broader shift underway across the industry. Pharmaceutical teams are recognizing that process development is not just a technical step, but a strategic lever for speed, quality, and regulatory success. As manufacturing becomes more complex — spanning small molecules, biologics, and emerging modalities — the need for scalable, data-driven infrastructure is only growing.

Scaling our vision

We are deepening our work in complex biologics and AI-led automation — advancing toward our long-term goal: a unified digital layer that supports the entire journey from discovery to commercial manufacturing, with consistency, scientific rigor, and automation.

Our team brings together scientists and engineers with backgrounds across the life sciences and technology sectors, united by the shared experience of building and scaling systems in some of the most complex and regulated environments in the world.

Powering the next generation of biopharma

As the industry faces increasing complexity — from new modalities to tighter timelines and evolving regulatory expectations — PolyModels Hub is helping development teams move faster with greater confidence.

"The pharmaceutical industry is undergoing a once-in-a-generation digital transformation. In just 18 months, our technology and exceptional team have delivered tangible value across multiple programs, expanding these collaborations to a global scale. We’re investing deeply in complex biologics and advancing our platform to empower scientists with the model-based solutions they deserve to transform molecules into medicines for the 21st century," said Antonio Benedetti, CEO & co-founder, PolyModels Hub.

Ben Wilkinson, CEO, Molten Ventures, added “PolyModels Hub is solving a real pain point for pharma teams, bringing together deep domain expertise and cutting-edge technology in a way that’s genuinely transformative. We’re proud to support Antonio B, Antonio Y, Harry and the team as they scale their impact across the industry. What impressed us most is the team’s blend of technical know-how and deep understanding of their customers’ challenges. They’ve built a solution that delivers value in weeks, not years, and its rapid adoption across the industry speaks volumes.”

“Despite the technological and scientific progress, a large part of pharma still runs on archaic lab processes, delaying patients’ access to life-changing medicines. We are privileged to be day one partners with PolyModels Hub as they redefine how the industry designs, tests, and improves drug development processes using data and automation”, said Alex Alexakis, Partner, Marathon Venture Capital.

PolyModels Hub operates at the intersection of science, engineering, and data. By connecting models, experiments, and decisions in a single environment, we are helping biopharma teams move from complexity to clarity — and ultimately, bring better medicines to patients faster.

About PolyModels Hub

PolyModels Hub is a biotech software company developing the digital backbone for biopharma process development. Its flagship platform, ModelFlow, integrates data, models, and workflows to help scientists and engineers design, simulate, and optimize pharmaceutical processes faster and more reliably. By bridging AI, modeling, and domain expertise, PolyModels Hub empowers development teams to deliver better medicines to patients, faster.

About Molten Ventures

Molten Ventures plc is one of the most active venture capital firms in Europe, developing and investing in disruptive, high growth technology companies. We believe it is our role to support the visionary entrepreneurs who will invent the future. We fuel their growth with our ‘energy’ in the form of truly patient capital, access to international networks and decades of experience building businesses. Currently, Molten Ventures is a shareholder in a diverse portfolio of companies including Revolut, Ledger and ICEYE. For more information please visit: www.moltenventures.com

About Marathon Venture Capital

Marathon Venture Capital is a seed-stage venture capital fund supporting ambitious founders in creating world-class technology companies. With over €175 million in assets under management, Marathon is the first investor in rapidly growing startups such as Causaly, Augmenta, Hack The Box, and Learnworlds. For more information, visit https://marathon.vc or contact info@marathon.vc.